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Home HPV Vaccines HPV Vaccines Researchers Believe HPV Vaccine Impacts Cervical Diseases in Australia

Researchers Believe HPV Vaccine Impacts Cervical Diseases in Australia

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Early indications indicate a large reduction in severe cervical diseases in young women following the introduction of Australia’s national HPV vaccine program in 2007.

Australia launched a national school-based HPV vaccine program in 2007 for all girls ages 12-13. Between 2007 and 2009 there was also a catch-up program for 14-18 year old girls.

Using data from the Victorian Cervical Cytology Registry (Victoria is Australia’s second most populous state and home to the largest city and capital, Melbourne), researchers found the incidence of high-grade cervical Girls Laughingdiseases decreased by nearly half among girls under age 18 in the first three years of the HPV vaccination program. “High-grade” diseases in this study were defined as cervical intraepithelial neoplasia (CIN) and adenocarcinoma in situ (AIS), both of which are considered precursors to invasive cervical cancer.

There was no reduction in low-grade diseases in any age group, nor high-grade lesions in age groups older than 18.

The investigators caution that more study is needed to confirm the reduction in disease is due to the vaccine, writing that a “linkage between vaccination and screening registries is needed to confirm that this ecological observation is attributable to vaccination…” Still, this is the first evidence that HPV vaccines work in the real world.

Brotherton J, Fridman M, May C, Chappell G, Saville A, Gertig D. Early effects of the HPV vaccination programme on cervical abnormalities in Victoria, Australia: an ecological study. The Lancet, 2011. 377(9783):2085-2092.